Gene information
Official symbol IL4R
Official full name interleukin 4 receptor
Gene type protein-coding gene
Chromosome16p12.1
Alias symbolCD124
Gene familyCD molecules; Interleukin receptors
Resources
Entrez Gene 3566
HGNC HGNC:6015
Ensembl ENSG00000077238
Vega OTTHUMG00000097015
UCSC uc002don.5
GO terms: 76 records
GO Description Category LogP Number of genes Detail
GO:0001562 response to protozoan GO Biological Processes -4.01585848 7 More
GO:0002532 production of molecular mediator involved in inflammatory response GO Biological Processes -6.20743023 5 More
GO:0002639 positive regulation of immunoglobulin production GO Biological Processes -6.83160707 8 More
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0002695 negative regulation of leukocyte activation GO Biological Processes -9.84552767 31 More
GO:0002703 regulation of leukocyte mediated immunity GO Biological Processes -18.0432682 27 More
GO:0002820 negative regulation of adaptive immune response GO Biological Processes -3.17098953 5 More
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -3.34951384 5 More
GO:0002825 regulation of T-helper 1 type immune response GO Biological Processes -5.99805120 6 More
GO:0002828 regulation of type 2 immune response GO Biological Processes -8.52846045 8 More
GO:0002830 positive regulation of type 2 immune response GO Biological Processes -7.53000143 6 More
GO:0002886 regulation of myeloid leukocyte mediated immunity GO Biological Processes -10.0272645 11 More
GO:0004896 cytokine receptor activity GO Molecular Functions -9.30297759 21 More
GO:0007162 negative regulation of cell adhesion GO Biological Processes -21.5212108 58 More
GO:0007292 female gamete generation GO Biological Processes -4.09618363 9 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0017157 regulation of exocytosis GO Biological Processes -7.48561663 15 More
GO:0022408 negative regulation of cell-cell adhesion GO Biological Processes -15.9068791 40 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0032642 regulation of chemokine production GO Biological Processes -25.2850711 37 More
GO:0033003 regulation of mast cell activation GO Biological Processes -4.83325597 6 More
GO:0033005 positive regulation of mast cell activation GO Biological Processes -4.00389964 4 More
GO:0033006 regulation of mast cell activation involved in immune response GO Biological Processes -5.56777868 6 More
GO:0033008 positive regulation of mast cell activation involved in immune response GO Biological Processes -4.62139945 4 More
GO:0042832 defense response to protozoan GO Biological Processes -4.13020121 7 More
GO:0043032 positive regulation of macrophage activation GO Biological Processes -14.1432953 16 More
GO:0043235 receptor complex GO Cellular Components -19.4198369 40 More
GO:0043300 regulation of leukocyte degranulation GO Biological Processes -5.75997337 7 More
GO:0043302 positive regulation of leukocyte degranulation GO Biological Processes -3.69512980 4 More
GO:0043304 regulation of mast cell degranulation GO Biological Processes -5.73056952 6 More
GO:0043306 positive regulation of mast cell degranulation GO Biological Processes -4.62139945 4 More
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation GO Biological Processes -5.90313372 12 More
GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation GO Biological Processes -2.82210951 5 More
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation GO Biological Processes -5.73056952 6 More
GO:0043627 response to estrogen GO Biological Processes -7.69647850 16 More
GO:0045580 regulation of T cell differentiation GO Biological Processes -7.18541630 25 More
GO:0045581 negative regulation of T cell differentiation GO Biological Processes -3.22341771 8 More
GO:0045582 positive regulation of T cell differentiation GO Biological Processes -5.99210992 10 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045620 negative regulation of lymphocyte differentiation GO Biological Processes -5.62617381 12 More
GO:0045622 regulation of T-helper cell differentiation GO Biological Processes -5.35296451 10 More
GO:0045623 negative regulation of T-helper cell differentiation GO Biological Processes -3.00303064 3 More
GO:0046634 regulation of alpha-beta T cell activation GO Biological Processes -7.20313216 11 More
GO:0046635 positive regulation of alpha-beta T cell activation GO Biological Processes -5.84288222 8 More
GO:0046636 negative regulation of alpha-beta T cell activation GO Biological Processes -2.81707928 4 More
GO:0046637 regulation of alpha-beta T cell differentiation GO Biological Processes -6.05306731 14 More
GO:0046638 positive regulation of alpha-beta T cell differentiation GO Biological Processes -5.69888611 7 More
GO:0046639 negative regulation of alpha-beta T cell differentiation GO Biological Processes -2.50427121 3 More
GO:0050777 negative regulation of immune response GO Biological Processes -11.1440698 32 More
GO:0050866 negative regulation of cell activation GO Biological Processes -13.9027363 39 More
GO:0050868 negative regulation of T cell activation GO Biological Processes -5.59075646 10 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051250 negative regulation of lymphocyte activation GO Biological Processes -7.76846228 25 More
GO:0060142 regulation of syncytium formation by plasma membrane fusion GO Biological Processes -2.86749174 6 More
GO:0060143 positive regulation of syncytium formation by plasma membrane fusion GO Biological Processes -2.55598907 3 More
GO:0060341 regulation of cellular localization GO Biological Processes -10.5933083 72 More
GO:0060627 regulation of vesicle-mediated transport GO Biological Processes -25.1756709 46 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0120161 regulation of cold-induced thermogenesis GO Biological Processes -19.1025541 38 More
GO:0120162 positive regulation of cold-induced thermogenesis GO Biological Processes -19.5569802 32 More
GO:0140375 immune receptor activity GO Molecular Functions -8.53513203 25 More
GO:1901739 regulation of myoblast fusion GO Biological Processes -3.76608029 6 More
GO:1901741 positive regulation of myoblast fusion GO Biological Processes -3.08353391 3 More
GO:1902106 negative regulation of leukocyte differentiation GO Biological Processes -7.27922558 19 More
GO:1903037 regulation of leukocyte cell-cell adhesion GO Biological Processes -23.2079690 66 More
GO:1903038 negative regulation of leukocyte cell-cell adhesion GO Biological Processes -10.2281373 27 More
GO:1903305 regulation of regulated secretory pathway GO Biological Processes -6.01402466 11 More
GO:1903307 positive regulation of regulated secretory pathway GO Biological Processes -2.97443173 8 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1903707 negative regulation of hemopoiesis GO Biological Processes -7.72888419 20 More
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation GO Biological Processes -5.84288222 8 More
GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation GO Biological Processes -2.23601792 3 More
GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation GO Biological Processes -5.27280402 6 More
KEGG pathways: 4 records
KEGG Description Category LogP Number of genes Detail
hsa04151 PI3K-Akt signaling pathway KEGG Pathway -29.3006421 73 More
hsa04658 Th1 and Th2 cell differentiation KEGG Pathway -5.18694144 15 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05321 Inflammatory bowel disease KEGG Pathway -16.3800424 16 More
Drug-Gene interaction
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Related drugs: 5 records
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_000418.4:c.223A>G genomics myocardial infarction[diagnosis] myocardial infarction Rosner SA et al. Hum Genet. 2005
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